The fever on the soles of the feet needs to be considered from both Chinese medicine and Western medicine: 1. From the perspective of Chinese medicine, the fever on the soles of the feet belongs to the fire evidence, which belongs to the deficiency fire, often caused by kidney deficiency and spleen deficiency, and the symptoms may also occur in the lower jiao fire, such as liver fire and hyperactive liver yang, which may also lead to fever on the soles of the feet. 2. From the perspective of Western medicine, the fever on the soles of the feet is an endocrine and metabolic dysfunction. The clinical signs and symptoms of fever in the palms and soles of the feet can occur during menopause in women, as well as in those with high catabolic rates, such as hyperthyroidism. Infectious diseases such as tuberculosis, connective tissue disease, dermatomyositis, and systemic lupus erythematosus can also present with clinical symptoms of fever in the heart of the feet.