High cholinesterase is dangerous because high cholinesterase marks five major systemic diseases: 1, the most common, such as central nervous system lesions will have demyelination changes, so cholinesterase will have a transient increase, which will be accompanied by the risk of cerebrovascular disease. 2, patients often have fatty liver, when cholinesterase will be elevated, so elevated cholinesterase in the digestive system will have a serious risk of fatty liver development. 3. diseases of renal nature, such as hyperthyroidism and other metabolic diseases can lead to increased renal load, so high cholinesterase can increase the risk of renal tubular acidosis. 4. certain blood diseases can also have high cholinesterase, such as hemolytic anemia and megaloblastic anemia, so high cholinesterase can also have a high risk of hematologic system. 5. there can also be connective tissue diseases, such as rheumatism and rheumatoid diseases, rheumatoid and other diseases are at high risk.