There are many reasons for weight loss and obvious wasting, commonly including digestive system diseases (such as gastric cancer), endocrine metabolic diseases (such as hyperthyroidism), etc. It is recommended to consult a doctor to find out the cause of the disease in time. 1. Digestive system diseases: digestive tract tumors such as stomach cancer can cause obvious weight loss, which may be accompanied by other digestive symptoms such as belching (burping), early satiety and so on. 2. Endocrine metabolic diseases: such as diabetes mellitus, thirst, polyuria, weight loss and other symptoms can occur. If hyperthyroidism, metabolism increases, weight loss can occur, accompanied by panic, fear of heat, sweating, anxiety, insomnia and other symptoms. When weight loss is obvious, you should consult a doctor in time to clarify the cause of the disease and treat it under the doctor’s guidance.