The need for medication for moderate to severe fatty liver depends on the liver function. 1. Most patients with moderate to severe fatty liver do not need medication if their liver function is normal. 2. If moderate-to-severe fatty liver combined with abnormal liver function is diagnosed as steatohepatitis, if it is not improved by reasonable exercise, adjusting the diet structure and limiting or prohibiting alcohol, it is recommended to give liver-protective treatment, and the commonly used oral drugs are dicyclomine, glycyrrhetinic acid preparation, polyenyl phosphatidylcholine, etc.