It is possible that hives in two year olds will heal on their own, but hives is an easily recurring condition and very few people heal on their own. Two-year-olds have an underdeveloped immune system, digestive system, and respiratory system, so it is possible that hives will gradually improve with age and changes in the individual’s constitution will occur. However, because of the relationship with the individual’s constitution, if the individual’s constitution does not change, hives may remain with the individual for the rest of his or her life. There are thousands of substances to which hives are allergic, including inhaled, ingested, and contact substances, as well as infections, which include bacterial and viral infections, and H. pylori stomach infections. In addition, there is a relationship with immune-related factors, such as abnormalities in thyroid function. Therefore, it is prone to recurrence and requires active and regular treatment, as well as a good attitude.