Gallstone attacks are usually able to achieve effective relief with aggressive treatment for 3-5 days. Due to individual differences, some patients do not do well with aggressive control and eventually need to consider surgery to achieve their goal. As the severity of each individual’s condition varies, the time for attack relief will also vary greatly. Gallstone attacks are commonly associated with the following conditions: 1. Acute complications: Gallstone attacks are commonly associated with acute inflammation, edema, and biliary tract infection of the gallbladder, which leads to the appearance of symptoms. In this case, timely antispasmodic and anti-inflammatory symptomatic treatment can effectively improve the symptoms, which can be effectively relieved in 3-5 days; 2, stone embedment: If the stone is embedded in the gallbladder duct, resulting in bile can not be discharged, the inflammation can not be lifted. Drug treatment can not effectively unblock the bile duct, the stone is still in the state of continuous embedding, symptoms can not be relieved, can only be considered through surgery to get effective treatment; 3, low immunity: some old and weak, low immunity of patients, biliary tract infection in the case of active anti-inflammatory still can not be controlled, and even aggravated, resulting in systemic infection and shock. In this case, timely puncture and drainage or surgical excision is needed to control the local infected lesion in order to prevent the aggravation of the disease. Therefore, the degree of gallstone attack varies from individual to individual and it is not possible to determine how many days it will take to get relief. The severity of the disease varies, and the treatment options chosen will also vary greatly. If conservative treatment for acute gallstones is not effective, early surgical excision should be considered to avoid aggravation of the disease.