Kidney disease refers to various diseases of the kidney. In the early stage of kidney disease, the most obvious symptoms include edema, urine color change, abnormal urine volume, back pain, gastrointestinal reactions, and weakness, but these are symptoms after the clear appearance of pathological changes and are not signs. 1. Edema: the function of the kidney is to excrete excess water and metabolic waste from the body. When kidney disease occurs, due to factors such as water and sodium retention and increased vascular permeability, the Patients can have body edema, especially the eyelids and lower extremities are most common; 2, urine color changes: when the kidney disease, there can be hematuria, the color of urine may change to wash water color, soy sauce color or strong tea color, etc., if the urine contains protein, but also accompanied by increased urine foam, and the foam is not easy to subside; 3, abnormal urine volume: abnormal urine volume, such as increased frequency of urine, urine reduction or no urine, are 4, back pain: back pain, may also indicate kidney disease, the most likely to cause back pain disease is polycystic kidney, chronic obstructive nephropathy, nephritis, etc.; 5, gastrointestinal tract reactions: when the kidney function is severely damaged, or the amount of urine protein, the presence of hypoalbuminemia and other conditions, due to toxins and water can not be discharged in a timely manner, will cause gastrointestinal edema, resulting in indigestion, loss of appetite, etc. In serious cases, it will also cause nausea, vomiting, gastrointestinal bleeding, etc.; 6. Lack of energy: Many patients with kidney disease have early symptoms that are not obvious, and some of them will have non-specific performance, such as lack of energy. It is recommended that when the above symptoms appear in the body, immediately go to the hospital for examination to clarify the cause, develop the corresponding treatment plan, and actively cooperate with the doctor for treatment. Daily, we should pay attention to regular rest, avoid overexertion and strenuous exercise, and eat a healthy diet.