HPV 16 positivity needs to be combined with TCT and further colposcopy will be arranged. Depending on the colposcopy, a vaginal biopsy will be taken if necessary, and depending on the biopsy pathology results, a decision will then be made on the next step of treatment. If the biopsy pathology is only suggestive of HPV infection, in this case you can apply Synflorin treatment. In general, it is necessary to pay attention to rest, enhance body resistance, eat more high-protein diet, go to bed after 10 pm, ensure sufficient sleep, keep your spirit happy, and don’t give yourself too much stress, all of which are helpful for the clearance of HPV16. If HPV16 is positive and the cervical biopsy pathology is problematic, further cervical conization surgery is needed, if necessary, depending on the situation.