In today’s accelerating pace of life, many people suffer from constipation, including the elderly, young people, and children. Occupations include all kinds of professions, such as drivers, office workers, students, etc. Have you ever tried not to have a bowel movement for several days? Have you ever experienced holding your face in the toilet, only to see the cannon, not gold; squatting until your legs are weak, but also can not be solved? You may be in pain to the point of picking the bowels with your hands? May have watched the face of the acne more and more war, the more uncontrollable? May have experienced the small stomach bloating unbearable? What exactly is the cause of constipation? The process of defecation in a normal person can be divided into two parts: the entry of feces into the rectum to produce the urge to defecate and the instruction to expel the feces. This is accomplished by the following four components: A. mechanical stimulation caused by the swelling of the fecal mass in the rectum, which causes the defecation reflex; B. propulsive contraction specific to the smooth muscles of the colon and rectum; C. relaxation of the internal and external anal sphincters; and D. contraction of the abdominal muscles and diaphragm, which leads to an increase in pressure in the abdominal cavity and causes the discharge of feces. Defects in any of the above can lead to constipation. There are many causes of constipation, and the following are some of the common causes. 1, diet and life factors: drinking food containing little fiber (to consider patients with few teeth and other factors) (especially some people do not like dietary fiber); low water intake or excessive sweating, little exercise or prolonged bed rest due to illness, lack of regular diet and bowel habits (such as often do not eat breakfast, irregular meals, irregular bowel movements), often artificially suppress the desire to stool (such as children often play to hold back stool, and School students, especially girls, hold their stools because of the shortage of toilet seats and the short time between classes, and they do not have time to go to the toilet when they are busy at work), and changes in the environment (such as business trips, travel, etc.). 2, mental factors: depression (depressed patients are prone to constipation even if they do not take antidepressants); mental illness, anorexia nervosa (for example, people who lose weight). 3, pharmacological: anticholinergic drugs (such as atropine, scopolamine), drugs for the treatment of psychiatric disorders (such as antidepressants), some narcotics and opiates, iron used clinically to supplement blood, bismuth and antacids (such as aluminum) used to treat stomach disorders, anti-Parkinsonian drugs, anti-hypertensive drugs (such as diuretics, ganglion blockers, calcium channel blockers, etc.), anticonvulsants (such as the treatment of epilepsy Some of the drugs) the abuse of some laxatives (such as if the guide tablets, detoxification capsules, intestinal rinse tea, rhubarb, senna), the use of some of the antidiarrheal agents used to treat diarrhea (Simethicone, montelukast). 4, endocrine, metabolic and collagen vascular disease: hypothyroidism, hypoparathyroidism, diabetes, hypokalemia, chronic renal failure, pregnancy (high incidence of constipation in pregnant women), porphyria (as long as the manifestation of photosensitivity, digestive symptoms, psychiatric symptoms), scleroderma, hypercalcemia, elevated prolactin, lower estrogen. 5, neuromuscular lesions: brain lesions are common for cerebrovascular accidents (cerebral hemorrhage, cerebral infarction), Parkinson’s disease, intracranial tumors; spinal lesions are common for cauda equina lesions, spinal cord spinal herniation, trauma (such as spinal cord trauma); peripheral neuropathy is common for diabetes mellitus, Hirschsprung’s disease (congenital disorder, part of the colon lack of nerve cells, unable to relax resulting in constipation), the Neurofibromatosis, abuse of stimulant laxatives causing damage to the terminal nerves of the intestinal mucosa. 6, functional lesions: outlet obstruction (such as obstructive defecation, pelvic spasm syndrome, internal rectal prolapse, pelvic floor hernia, puborectalis syndrome, perineal descent syndrome, rectal prolapse, internal sphincter loss retardation, isolated rectal ulcer syndrome, etc.); slow transmission type constipation (including colonic weakness). Since there are many causes of constipation, each patient with constipation needs to find his or her own causes and treat them early and symptomatically, and not to take or even abuse various laxatives without authorization to avoid causing more damage to the organism.