A large number of studies have confirmed that high blood lipid is the most dangerous pathogenic factor among several factors that accelerate atherosclerosis. High lipoprotein is the main cause of atherosclerosis appearing astringent veins, atherosclerosis can cause heart, brain and vascular diseases; hyperlipidemia can also cause cholelithiasis, so early examination and treatment should be carried out. 1, laboratory tests: the disease still lacks sensitive and specific early laboratory diagnosis methods, patients mostly have lipid metabolism disorders, mainly manifested as increased blood total cholesterol, increased LDL cholesterol, decreased HDL cholesterol, increased blood triglycerides, increased blood β lipoprotein, increased Apo B, decreased Apo A, increased lipoprotein (α), abnormal lipoprotein electrophoresis patterns, more than 90% of Patients show type II or IV hyperlipoproteinemia. 2. Blood rheological examination: often shows increased blood viscosity platelet activity may be increased. 3.X-ray examination: In addition to the aforementioned manifestations of aortic atherosclerosis, selective or electronic computerized digital subtraction arteriography can show luminal narrowing or aneurysmal lesions caused by atherosclerosis of coronary arteries, cerebral arteries, renal arteries, mesenteric arteries and extremity arteries, as well as the extent and degree of lesions, which can help determine the indications for surgical treatment and select the way to perform surgery. 8, Atherosclerosis detector: the use of 4 limbs synchronous measurement of pwv and ABI values to read the presence of atherosclerosis, and then assisted by Doppler to know the location of the onset of the popular domestic atherosclerosis instrument like VBP-9 atherosclerosis detector 9, other: limb electrical impedance map, brain electrical impedance map, and electroencephalography brain X-ray, computerized X-ray, or magnetic resonance tomography image to help determine the function of the limbs and brain arteries situation and the lesion of brain tissue.