Glucocorticoids can be divided into long-, medium- and short-acting categories according to their duration of action. The aforementioned dexamethasone belongs to the long-acting category, prednisone (prednisone) belongs to the medium-acting category, while the short-acting ones include hydrocortisone, etc. Glucocorticoids have been used in clinical practice for nearly half a century and are mainly used in the following areas: 1. Patients with various causes of adrenocortical hypofunction need physiological doses of hormones to maintain their normal material metabolism and vital activities, including glucocorticoids. 2. 2. Many autoimmune diseases and diseases caused by in vivo immune disorders, such as systemic lupus erythematosus, lupus nephritis, purpura nephritis, primary nephrotic syndrome, etc., also require pharmacological doses of glucocorticoids for their strong immunosuppressive and regulatory effects, and they are often preferred. 3. In addition, hormones have a role that is difficult to be replaced by other drugs in anti-shock, in the rescue of severe infections, in the treatment of allergic diseases, and even in the chemotherapy regimen for certain hematological tumors. The most common ones include weight gain and mood swings. Weight gain is caused mainly by water retention in the body at first, and later because glucocorticoids increase your appetite and increase the accumulation of fat. Some people feel upbeat and emotional after taking glucocorticoids, while others feel sad, anxious or depressed, nervous or have insomnia. You should tell your doctor if you have had a serious mental illness in the past. 2. Patients who have been taking the drug for more than a few weeks may experience mild weakness in the limbs, hair loss or excessive hair growth, facial hairiness in women, acne, rounding of the face (full moon face), easily broken skin wounds that do not heal easily, slow growth and osteoporosis in children or adolescents. 3. For patients who have been taking glucocorticoids for several weeks to months, especially those who apply medium to high doses, they may occasionally experience elevated blood pressure and blood sugar, red or purple skin markings, irritable gastrointestinal tract or gastric ulcers, especially when combined with aspirin or non-steroidal anti-inflammatory drugs. If you suffer from the above diseases and need to take glucocorticoids, please be sure to consult with your doctor before taking the medication. 4. Patients who take medium or higher doses of glucocorticosteroids for a long time may individually experience some rare side effects such as osteoporosis and serious infections due to decreased immunity. However, as long as you take the medication carefully according to medical advice and pay attention to maintaining a healthy lifestyle (such as exercising regularly, paying attention to ensuring nutrition and proper rest), the possibility of these drugs causing side effects will be relatively small. The following suggestions can help you minimize the side effects of glucocorticosteroids: 1. Take the medication strictly as prescribed by your doctor, and do not increase or decrease the dosage or stop the medication on your own unless specifically instructed by your doctor. 2. 2. Go to the hospital for regular review in order to prevent side effects or detect them early. If you feel that you are experiencing side effects, especially if you have symptoms such as high fever and chills, shivering, severe joint pain or bone pain, persistent blurred vision, severe muscle weakness; special abnormalities in your mood or behavior, please get in touch with your doctor. 3. Establish healthy eating habits, eat less oily and high-salt foods, and do not consume too many carbohydrates. However, to consume enough calcium and vitamin D, you can seek the advice of your doctor. 4.Proper exercise to keep your bones and muscles healthy. Exercise should be measured and not overworked. If you have been using the medication for more than a few weeks, it is dangerous to stop it suddenly because after continuous use, when you encounter external stimuli that require glucocorticoids, the adrenal glands will slow down their response to the stimuli; moreover, during the process of reducing the dosage, your condition may recur. 6. If you happen to be pregnant or breastfeeding, you should consult your doctor as soon as possible.