The generic name of Nosyntho is sacubatril valsartan sodium tablets, which have been effective in heart failure and hypertension after one year of consumption, but there are individual differences in efficacy. 1.Sacubitril valsartan sodium tablets produce cardiovascular and renal effects and reduce the risk of cardiovascular death as well as hospitalization for heart failure. It is used for chronic heart failure in adults (with reduced ejection fraction) and also in the treatment of hypertension. 2. It can have good efficacy after one year of administration, but efficacy varies depending on the condition, individual constitution and other influences. 3. Adverse reactions such as hypotension, angioedema, hyperkalemia and renal impairment can be seen with Sacubitril valsartan sodium tablets. 4. The drug is contraindicated in people who are allergic to the active ingredient of the product, in people with hereditary or idiopathic angioedema, in people with severe hepatic impairment, cholestasis, biliary cirrhosis, and in people with mid-term and late-term pregnancy. The use of this product for the treatment of disease need to be standardized under the guidance of a doctor, do not blindly use their own medication.