Pre-operative preparation: (1) Routine pre-operative examination: electrocardiogram, blood and urine routine, blood biochemistry, infectious diseases, coagulation function, blood group. (2) Special examination: MR examination of knee joint (3) Examination and treatment of common medical conditions: hypertension, diabetes mellitus, coronary heart disease, thrombotic disease; long-term medication registration. (4) Search for and treatment of systemic infectious lesions: tinea pedis, skin infections, etc. (5) Pre-operative knee function score. Postoperative management (1) local compression bandage and ice for 3 days; (2) functional exercises for leg raising after awakening from anesthesia; (3) negative pressure drainage was left in place for about 1 day, and was removed when the drainage flow was less than 25 ml; (4) the compression bandage was removed on the 3rd day, and functional exercises for joint flexion were performed; (5) intravenous antibiotics were used for 3 days; (6) auxiliary materials were changed on the 4th day, and the patient could be discharged from the hospital; (7) postoperative crutches were removed on the 4th-14th days. (7) crutches on the ground 4-14 days after surgery, stitches removed 10-12 days after surgery; (8) further rehabilitation training see “rehabilitation guidance for patients with knee replacement”. Postoperative follow-up and registration: (1) Fill in the postoperative follow-up and registration form (2) Postoperative knee function score