Soft tissue injury, bursitis, trauma and so on are the causes of pain on the outside of the knee when pressed. 1. Soft tissue injury: due to trauma, friction, extrusion and other external factors, caused by the patient’s knee or the surrounding soft tissues, such as muscles, ligaments, fascia, etc., injury, which triggered the patient to appear on the outside of the knee pain when pressed. 2. Bursitis: due to long-term strenuous exercise, exertion, standing, etc., resulting in the patient’s knee bursa constant friction, extrusion, the formation of aseptic inflammatory infection, when the inflammatory factors continue to stimulate, will trigger the patient to appear on the outside of the knee when pressed on the case of pain. 3. Trauma: due to impact, fall, fall from a height and other factors, the patient’s knee is subjected to external forces, fracture, so that the knee bone, meniscus and so on the destruction, which leads to the patient to appear on the lateral side of the knee when pressed on the symptoms of pain. There are many reasons why patients experience pain when pressing on the outside of the knee, and it is recommended that patients go to the hospital in time to complete the relevant examinations, clarify the cause of the disease, and follow the doctor’s instructions for treatment.