Gestational diabetes mellitus occurs in some women after pregnancy due to changes in the body’s metabolism, seriously jeopardizing the life and health of the pregnant woman and her fetus. It is crucial for pregnant women to take the correct method to control blood pressure during pregnancy. The current clinical methods of blood glucose control package: diet and exercise control methods, insulin control methods. It is necessary to choose the appropriate approach to lowering blood sugar according to the fluctuation of blood sugar during pregnancy. In general, if a pregnant woman’s blood sugar during pregnancy is mildly elevated, then she can take diet and exercise control methods. During the period of blood sugar control, pregnant women need to adopt a diabetic diet, control the total energy of the diet, eat small meals, pay attention to the nutritional combination of the diet. Diet control at the same time, assisted by appropriate exercise. If the pregnant woman’s blood sugar is high, then she needs to use insulin to lower blood sugar. Since the application of drugs during pregnancy needs to consider the effect of drugs through the placenta to affect the fetus, therefore, subcutaneous injection of insulin is mostly used to lower blood glucose during pregnancy, instead of using oral medication to lower blood glucose. The dosage of insulin needs to be adjusted according to the changes in blood glucose monitoring. If blood glucose control is not good, it is necessary to consult the endocrinology department of the local hospital for professional blood glucose regulation. In summary, blood glucose regulation during pregnancy requires dietary control, appropriate exercise and, if necessary, insulin therapy.