Different hypoglycemic drugs have different ways of taking them, and there is no completely unified standard. For example, sulfonylureas should be taken orally with water half an hour before breakfast, while metformin should be taken in the middle of a meal, controlled-release tablets need to be swallowed whole, and chewable tablets need to be chewed and taken orally, etc. It is recommended that you consult your doctor for the specific method of taking. 1. Taking time: sulfonylureas should be taken half an hour before meals to increase the insulin receptor sensitivity of tissue cells; metformin should be taken during meals to reduce gastrointestinal reactions, and alpha-glucosidase inhibitors should be taken with the first starch. 2. Method of taking: If it is a controlled-release tablet or slow-release tablets of hypoglycemic drugs should be swallowed intact, should not be broken, crushed or chewed to take. Acarbose chewable tablets need to be chewed with food, and if it is a capsule, it should be swallowed whole before meals. Patients who need to take hypoglycemic drugs should use them under the guidance of a doctor, and should not use them blindly on their own.