Infant fever for the first time should be strengthened care, reasonable antipyretic symptomatic treatment, and clarify the causes of fever for the treatment of the cause. 1. Strengthen care: for the first fever baby, such as has added complementary foods, can be appropriate to drink more water, according to the fever baby extremity temperature and other conditions of the correct increase or decrease in clothing, such as the baby extremities end cold, or accompanied by shivering, need to pay attention to warmth, such as extremity end temperature warming and sweating, need to be appropriate to reduce the blanket, pay attention to cooling. 2. Symptomatic treatment: for the first fever baby such as temperature over 38.5 ℃ with obvious discomfort, can be used under the guidance of the doctor acetaminophen and other antipyretic drugs, need to pay attention to 2 months of age babies can not be safe antipyretic drugs can be used, can be used in the form of warm water wiping physical cooling. 3. Define the cause of the disease and carry out the treatment: such as acute upper respiratory tract infections, viral infections caused by oral pediatric cold and flu granules, four seasons antiviral combination of drugs, bacterial infections caused by the use of antibacterial drugs for the treatment of commonly used drugs, including cefaclor, cefixime and so on. The above drugs need to be used under the guidance of a physician, avoid self-medication. There are many other causes of fever in babies, and it is recommended to actively consult a specialist to evaluate the condition and guide the treatment.