What are the common sites of ovarian cancer metastasis?

  Local spread and metastasis of ovarian cancer and abdominal implantation: Local spread and metastasis of ovarian cancer are mainly through contact infiltration and direct spread. Generally, cancer cells penetrate the ovarian envelope or ectopic cancer cells are shed and scattered in the pelvic cavity. Commonly involved sites are fallopian tubes, uterus, bladder, rectum, sigmoid colon and other pelvic peritoneum. Among them, pelvic peritoneum is the most commonly implanted site of ovarian cancer, followed by uterine rectal metastasis, liver surface, subdiaphragm, mesenteric surface, intestinal wall, greater omentum and peritoneum of each wall, etc. Ovarian cancer metastases may also appear.  1.Pelvic peritoneal metastasis of ovarian cancer: pelvic peritoneal metastasis of ovarian cancer is mainly caused by ascites symptoms caused by ovarian cancer. The peritoneum and organ plasma of pelvic and abdominal cavity can be planted by ovarian cancer cells, especially in the diaphragm, lateral sulcus of colon, mesentery, intestinal plasma membrane, bladder plasma membrane and rectal recess of uterus. Most of the implanted cancer foci are in the shape of small granules, or nodules, or masses of different sizes.  Ovarian cancer metastases to uterus and adnexa: uterus is the close neighbor of ovary. 16%-18% of ovarian epithelial cancers are accompanied by uterine metastases, and ovarian epithelial cancers, especially plasma cancers, have a fairly high bilaterality, up to 60%. The infiltrative growth of ovarian cancer often causes the uterus and both adnexa to form an integrated situation.  3.Intestinal metastasis of ovarian cancer: Intestinal metastasis of ovarian cancer is more common in the spreading metastasis of ovarian cancer, mostly the direct invasion of pelvic cancer cells.  4.Metastasis of ovarian cancer to the greater omentum: The chance of ovarian cancer, especially epithelial cancer, to metastasize to the greater omentum is large, about 23%-71%. Most of the metastatic cancer cells are found in the large omentum during microscopic examination with normal appearance. A large number of ovarian cancer cells metastasizing to the greater omentum will accumulate into a huge mass, and patients will experience abdominal distension, abdominal pain and heaviness, which will have a certain impact on the abdominal chemotherapy of ovarian cancer.  5. Liver and spleen metastasis of ovarian cancer: there are often tiny implantation nodules on the surface of liver and spleen, and sometimes there are ovarian cancer tumors spreading and metastasizing in the hepatic and splenic flexures of transverse colon and adhering to liver and spleen, or invading to liver and spleen.  Lymphatic metastasis of ovarian cancer: Lymphatic metastasis is one of the important ways for ovarian cancer to spread and metastasize. There are three main ways for lymphatic metastasis of ovarian cancer: 1. lymph nodes along the ovarian vessels terminate upward at the parietal aorta, which is located between the abdominal aorta and the renal artery, called the upward route. 2.  The lymphatic vessels come out from the ovarian portal between the two lobes of the broad ligament and terminate in the internal, external and inter-iliac lymph nodes, which is called the downward route, and then through the common iliac and to the para-aortic lymph nodes. When the upward route is obstructed, the lymphatic fluid may reflux to the pelvic lymph nodes or form a collateral circulation. Usually, both upward and downward routes exist simultaneously.  3. The ovarian lymphatic vessels follow the round ligament and drain into the external iliac lymph nodes and inguinal lymph nodes, this metastatic route is relatively rare.  Bloodstream metastasis of ovarian cancer is not very common in the spread of ovarian cancer. Bloodstream metastasis of ovarian cancer is usually formed when ovarian cancer cells enter the blood vessels directly and the blood stream infiltrates into the distant organs. The other way is that ovarian cancer cells first enter the lymphatic vessels to form lymphatic metastasis, and then enter the blood vessels to form hematogenous metastasis.  What are the common sites of late stage ovarian cancer metastasis? What are the Chinese herbal medicines for the treatment of advanced ovarian cancer metastasis? It is difficult to completely cure ovarian cancer metastasis in advanced stage, but if conservative Chinese medicine treatment is adopted, most of them can control the development of the disease, reduce the pain and achieve the purpose of long-term survival with tumor. Chinese medicine has long-lasting effect and can help to eliminate evil without harming positive, and can also regulate immune function and restore patients’ physical strength while killing cancer cells. In the treatment of ovarian cancer in advanced stage, they can combine the surface and the inside of the body, and treat both the symptoms and the root cause at the same time, and they are cheap.