Cerebral white matter sparing is due to chronic brain in a state of ischemia and hypoxia, resulting in demyelinating lesions in the white matter of the brain, which manifests as cerebral white matter sparing. For this condition, patients should control the progression of cerebral atherosclerosis and improve the state of ischemia and hypoxia in the brain. The main thing is to control hypertension, hyperlipidemia, diabetes, and homocysteine. If you have a bad lifestyle of smoking and drinking, you must avoid it, because smoking will aggravate the damage of vascular endothelium and lead to the aggravation of cerebral atherosclerosis, which will easily lead to cerebral white matter thinning symptoms. Patients with cerebral leukodystrophy will mainly manifest clinically as drowsiness, lack of wakefulness, and headache. If cerebral leukodystrophy is severe, patients will show memory loss, cognitive decline, and poor control of urine and stool.