Diarrhea with drainage-like feces may be associated with bacterial infectious diseases, rotavirus enteritis, and cholera, and can be treated with levofloxacin, ciprofloxacin, or rehydration solution. 1. Bacterial infectious diseases: Antibacterial drugs sensitive to pathogenic bacteria should be taken, such as levofloxacin, mephedrone, ciprofloxacin, etc. Meanwhile, oral rehydration salts, berberine hydrochloride, potassium, magnesium, calcium, etc., should be added to alleviate the symptoms, and probiotics, such as bifidobacteria, can be taken orally to restore the balance of the intestinal flora. 2. Rotavirus enteritis: most of the disease is mild and self-limiting, mainly for diarrhea and dehydration treatment, such as rehydration, correction of electrolyte disorders and acid-base imbalance. 3. Cholera: an acute gastrointestinal infectious disease caused by Vibrio cholerae. Treatment mainly includes strict isolation, timely rehydration and medication, including ciprofloxacin, norfloxacin, doxycycline and so on. The above drugs are prohibited for those who are allergic to them and should be taken in accordance with the doctor’s instructions. There are many other causes of diarrhea and drainage-like feces, it is recommended to go to the regular hospital in time, after clarifying the cause of the disease, under the guidance of the doctor for targeted treatment.