Urticaria is often accompanied by intense itching in the clinic, and patients can immediately apply antihistamines orally for relief, commonly used are loratadine, cetirizine, paracetamol, ibastine tablets, fexofenadine, etc. Most patients with acute urticaria can effectively relieve the intense itching of the skin after taking oral antihistamines. Patients can also apply topical medications for relief, such as applying glyburide lotion with glucocorticoid ointment topically, which can also provide good relief. However, patients with acute urticaria have more severe attacks that can lead to acute urticaria all over the body, which can be relieved by intravenous application of calcium gluconate, glucocorticoids, and intramuscular injection of finasteride.