Acute urticaria itself belongs to an acute allergic disease, the whole body can quickly appear edema-like wind masses, raised on the skin, accompanied by intense itching, and in severe cases, accompanied by edema of the eyelids, lips, and vulva area. By choosing topical creams, one can apply glyburide lotion or zinc oxide cream. Such medications applied to the skin surface can effectively make the efflorescence-like changes subside and can relieve itching, thus improving one’s quality of life. But ultimately, oral medication is needed for treatment. Oral desensitizing drugs, such as levocetirizine hydrochloride tablets, loratadine citrate capsules, epinephrine hydrochloride, etc., are needed, which, after intake, can effectively stabilize the cell walls of mast cells and prevent the mast cells from degranulating, thus preventing the cell contents from accumulating under the skin, which will prevent the appearance of the wind-blown changes and thus achieve the treatment The purpose of the treatment is to prevent the appearance of the wind-like changes.