Lower creatinine can be achieved by eating more lean meat, and in the long run, it is recommended to increase the amount of muscle in the body by engaging in more weight-bearing exercise. Creatinine is a product of muscle metabolism, and this muscle includes both muscle in the body and exogenously ingested lean meat. Therefore, patients with low creatinine can eat more lean meat, which is metabolized to produce creatinine. But in the long run, you can increase the amount of muscle in your body by participating in more weight-bearing exercises, such as squats, push-ups, sit-ups and so on, so that creatinine will rise. During pregnancy, due to the increase in kidney size and glomerular filtration rate, creatinine is excreted from the body in large quantities, which will also lead to low creatinine. This situation does not need special treatment, and with the end of pregnancy, creatinine will gradually return to normal. It should be emphasized here that the decrease of creatinine is not of great clinical significance, while the increase of creatinine is of greater clinical significance, suggesting renal failure.