【Abstract】 Objective: to investigate the clinical value of laparoscopic ultrasound in laparoscopic partial nephrectomy for central renal tumors. METHODS: Ten cases of central type renal tumors undergoing laparoscopic partial nephrectomy assisted by laparoscopic ultrasound were retrospectively analyzed. All patients were diagnosed with renal tumors on preoperative imaging examinations such as ultrasound, CT and/or MR, and the tumors were located in the renal parenchyma without obvious convexity. There were 6 males and 4 females, aged 10-62 years (mean 45.4 years), 5 cases were located in the central part of the kidney, 1 case was located in the upper pole of the kidney, and 4 cases were located in the lower pole of the kidney, and the tumor diameter ranged from 1.1 to 3.5 cm, with a mean diameter of 2.6 cm. RESULTS: Intraoperative ultrasound during laparoscopic surgery was used to locate the tumor location, size, border and blood supply in real time, to determine the extent of the renal tumor resection, and the ultrasound was re-reviewed after the resection, to ensure the margins of the cuts negative. Postoperative pathology returned 9 cases of renal cell carcinoma and 1 case of nephrolithiasis, and all margins were negative. CONCLUSION: Intraoperative LUS can provide real-time images to assist surgeons to accurately locate central renal tumors embedded in the renal cortex, provide real-time evaluation of the tumor, reduce intraoperative bleeding, guarantee negative margins, and provide effective guarantee for surgical safety.