Treatment of gynecological tumors with Gui Zhi Fu Ling Wan plus reduction

Gynecological tumors are common and frequent diseases that seriously threaten women’s health, and there are benign and malignant tumors, such as uterine fibroids and ovarian cysts among benign tumors, and cervical cancer and ovarian cancer among malignant tumors. Chinese medicine has a long history of treating gynecological tumors, and many effective experiences have been summed up by medical practitioners in the past generations. Gui Zhi Fu Ling Wan was firstly found in Zhang Zhong Jing’s “The Essentials of the Golden Horoscope”, the author used Gui Zhi Fu Ling Wan plus and minus in the clinical treatment of gynecological tumors, with outstanding efficacy, is introduced as follows. 1, Gui Zhi Fu Ling Wan formula and modern pharmacological effects of the “Golden Kui” “Women’s pregnancy disease pulse evidence and treatment of the twentieth” mentioned in the “women have a disease, menstrual break in less than three months, and get more than leakage, the fetus moving on the umbilicus, for the symptoms of chronic harm. Pregnancy in June, the first three months when the menstrual water conservancy, the fetus also. The next blood, after the break in March [also. So the blood is more than one, its symptoms do not go so, when the symptoms, Gui Zhi Fu Ling Wan main.” This article discusses the identification of pregnancy and disease and the treatment of disease leakage, and clinical research in recent years has shown that the application of this formula is not limited to pregnancy, all menstrual, fetal and obstetric disease caused by the disease block can be used. Gui Zhi Fu Ling Wan formula consists of Gui Zhi, Fu Ling, Peony Peel (remove the heart), Peony, Tao Ren (remove the tip of the skin), plus honey refined into a pill. The formula in the cinnamon branch to warm the Yang, to promote blood flow and disperse blood stasis as the ruler; white peony nourish the liver and Ying, slowing down the pain, red peony blood stasis for the minister; peach kernel, peony peel blood stasis for the adjuvant; Poria strengthens the spleen and Qi, nerves the heart and calm the mind, and cinnamon branch with the use of warm Yang open knot, cut evil and calm the fetus as the make. The combined use of all drugs, the effect of blood circulation, eliminate stasis, eliminate the symptoms of the effect. Modern pharmacological studies have confirmed that: Gui Zhi Fu Ling Wan has the effect of inhibiting platelet aggregation, reducing the viscosity of the whole blood, relieving uterine spasm, analgesia, etc. It can also improve microcirculation, enhance the immunity of the body, inhibit chronic proliferative inflammation, and has the effect of dilating peripheral blood vessels, lowering blood pressure and anti-inflammatory, hydrophobic, etc. Modern clinical use is widely used in the treatment of gynecological blood stasis evidence, uterine fibroids, chronic pelvic inflammatory disease and other masses, functional bleeding of irregular endometrial exfoliation, endometriosis, ovarian cysts, dysmenorrhea, etc. In Chinese medicine, gynecologic tumors are found in “obstruction”, “accumulation”, “stone obstruction”, “intestinal mushroom”, and “leakage”. In Chinese medicine, gynecological tumors are found in “obstruction”, “accumulation”, “stone obstruction”, “intestinal mushroom”, “leakage”, “five-colored miscellaneous belt” and other symptoms. For example, in Su Wen? Bone empty theory: “The Ren vein is a disease, and the woman has obstruction in the abdomen.” Ling Shu? Water distension” says: “The stone obstruction is born in the uterus, and the cold air comes to the Zi Men, the Zi Men is closed, the Qi cannot be passed, the bad blood is not diarrhea when it is diarrhea, [to stay and stop, and it gets bigger day by day, it looks like a cup, and the menstruation does not fall at the right time.” There are many causes of gynecological tumors, and the Nei Jing states that the cause of the stone obstruction is due to “cold qi visiting the Zi Men and the Zi Men being blocked”, resulting in “qi not being able to pass, and the malignant blood not being diarrhea when it should be, [so that it stays stopped]”. The Treatise on the Origin of Diseases points out that “women’s illnesses are different from those of their husbands, not only because of dietary disorders”, but also “because of cold in the deficient organs after childbirth, or because of excessive cold in the menstrual flow”, and therefore “they are mostly caused by blood and qi. “The eight obstructions are all caused by the birth of a child, the flow of the moon, and the irregularity of the blood and essence”; “A woman’s meridians and channels of glory and health are cut off and inaccessible, so the evil qi can enter and merge with the organs”; and: ” If a woman gives birth to a new baby, she starts to walk before the tenth month, and if she washes too early …… if she lives in a wet seat, she will become an obstruction”; if “the woman is under the moon, the bad blood is not finished, she is weak and exhausted, and she walks fast with the summer heat…. …the water of the moon flows horizontally, and it is diffused into other organs and does not go away, there is heat because it gives rise to dry obstruction”; “The woman’s water of the moon comes several times on the same day but she is sad and worried …… and her heart is indistinct and unsettled… …the spirit of the wandering dead,” then “the birth of the gathering of the obstruction”. The Ming Dynasty doctor Zhang Jinyue summed up what the previous people said and suggested that the evidence of obstruction is “blood stagnation as stasis, only women have it. The evidence is either from menstruation or postpartum, or from internal injury and blood stagnation, or from worry and spleen injury, qi deficiency and blood stagnation, or from accumulation of labor and weakness, qi weakness and inaction, always from blood movement, the remaining blood is not purified, and once there is a rebellion, the stagnation accumulates day by day, and gradually accumulates, and gradually becomes a disease.” In summary, the occurrence of gynecological tumors is mainly due to the inadvertent menstruation after childbirth, the internal invasion of wind, cold, dampness and heat, or the seven emotions and internal injury of diet, resulting in the malfunction of the internal organs, the deregulation of qi and blood, the damage to the ramifications, stasis of blood, phlegm, dampness and other tangible evil, stagnation in the abdomen, the cell, the ramifications, the accumulation of knots, and gradually become. Women suffer from the disease, especially after childbirth and menstruation without paying attention to the regulation, while not paying attention to the hygiene of sexual life, early marriage, premature birth, multiple births and sexual life disorders, is also one of the important reasons for the occurrence of gynecological tumors. Thus, the characteristics of gynecological tumors can be categorized as weakness of positive qi, stagnation of qi, blood stasis, phlegm and dampness, and the accumulation of evil toxins, i.e., deficiency, stasis, phlegm and toxins. Weakness of vital energy includes weakness of internal organs, Qi and blood. The internal organs are mainly the kidney, liver and spleen. Treatment should be based on the identification of deficiency of the evil and the real, and the differentiation of deficiency, stasis, phlegm and toxicity. The main principles of treatment are to support the root (including nourishing the kidneys, tonifying the kidneys, strengthening the spleen and stomach, draining the liver, nourishing the blood, regulating the flushing), promoting the flow of qi and blood, resolving phlegm and dampness, and detoxifying and dispersing nodules. In summary, the treatment of gynecological tumors should be a combination of evidence and disease identification, to invigorate blood circulation, eliminate stasis and disperse nodules as the main method, can use Gui Zhi Fu Ling Wan plus or minus. For benign tumors such as ovarian cysts and uterine fibroids that manifest Qi stagnation and blood stasis, Xiangling Wan should be added to move Qi and disperse the nodules; if the tumor is characterized by phlegm and blood stasis, Er Chen Tang should be combined to regulate Qi and resolve phlegm, break down the stasis and disperse the nodules; if the tumor is characterized by kidney deficiency and blood stasis, the formula should be combined to tonify the kidney and activate blood to eliminate the symptoms and nodules. For ovarian cancer, cervical cancer and other malignant tumors with Qi stagnation and blood stasis, combining Gui Zhi Fu Ling Wan and Di Diaphragmatic Expelling Stasis Tang is recommended to move Qi and invigorate Blood, dispel stasis and disperse nodules; for damp-heat and stasis, combining Si Miao San to clear heat and dampness, resolve stasis and detoxify; for liver and kidney yin deficiency, combining Liu Wei Di Huang Wan to tonify the kidney and nourish Yin, detoxify and disperse nodules; for spleen and kidney yang deficiency, combining Ginseng and Bai Zhu San with Radix et Rhizoma Polygonati, Boneset and Dry Lotus Grass to strengthen the spleen and warm the kidneys, tonify the middle. To strengthen the spleen and warm the kidneys, and tonify the middle and vital energy. In the treatment of malignant tumors, emphasis should be placed on detoxification and dispersion of nodules, while taking care of the spleen and stomach, and taking into account the concurrent evidence, in order to achieve the effect of treating both the symptoms and the root cause, and supporting the righteousness and eliminating the evil. During gynecological malignant tumor surgery and radiotherapy and chemotherapy treatment with Gui Zhi Fu Ling Wan, it can increase the sensitivity to radiotherapy and chemotherapy, reduce the toxic side effects of radiotherapy and chemotherapy, and achieve rapid recovery. As surgery consumes qi and blood, postoperative patients mostly show deficiency of both qi and blood, or qi and yin, and spleen and stomach disorders, so it can be combined with Xiang Sha Liu Jun Zi Tang and Ba Zhen Tang to regulate the spleen and stomach, benefit qi and fix the surface, nourish yin and generate fluid, which helps the body recover as soon as possible. Patients undergoing chemotherapy, the appearance of decreased appetite, nausea, etc., mostly with Fu Ling Gui Zhi Wan with spleen and stomach method of treatment; chemotherapy-induced bone marrow suppression, can be combined with supplementation and reduction of Teng Zhong Yi Qi Tang; radiotherapy-induced adverse reactions are mainly heat and toxin injury to yin, Qi deficiency, blood stasis, stasis poisoning heat and other evidence, treatment to clear heat and detoxification, nourishing Yin and fluid, with Gui Zhi Fu Ling Wan blood stasis, can achieve the effect of radiotherapy. 4, Gui Zhi Fu Ling Wan plus or minus to identify and treat gynecological tumors case example Gui Zhi Fu Ling Wan plus or minus to identify and treat gynecological tumors case 1: patient Liu, female, 43 years old, first diagnosed on September 19, 2007. Complaint: 2 years after uterine fibroid surgery, physical examination revealed a cystic occupying lesion in the right adnexa. Symptoms: abdominal distension, nasal distension, sleepiness, bowel movement. The tongue is light and fat, with thick yellow coating and thin pulse. Ultrasound at the local hospital showed a 9.5×9.0 cm and 4.5×2.5 cm liquid dark area in the right adnexal area, which was considered an ovarian cyst. TCM diagnosis: Qi stagnation and blood stasis. The treatment is to dredge the liver and disperse nodules, invigorate blood and move Qi. Prescription: Radix Codonopsis pilosulae 25g, Poria cocos 25g, Peach kernel 15g, Radix Paeonia lactiflora 10g, Peony bark 10g, Curcuma longa 15g, Cinnamomum cassia 5g, Radix et Rhizoma gastrodiae 10g, Penetrating stone 30g, Dandelion 30g, Leeches 10g, Turtle worms 15g, Qomai 30g. 1 dose daily with water decoction, divided into 2 doses in the morning and evening for 20 d. Ultrasound on October 9, 2007 showed that the right adnexa showed The formula was continued until November 21, 2007, when the ultrasound was repeated: no significant abnormality was seen in the bilateral adnexal area, and there has been no recurrence since the follow-up. Gui Zhi Fu Ling Wan plus and minus for gynecological tumors Case 2: Patient Chen, female, 63 years old, was first diagnosed on May 13, 2006. Complaint: 4 years after right breast cancer surgery, uterine fibroids were found on physical examination. The patient underwent surgery for right breast cancer in 2002. Pathological examination showed: invasive ductal carcinoma of the breast. After postoperative radiotherapy and 6 cycles of chemotherapy (chemotherapy regimen of cyclophosphamide + adriamycin + fluorouracil), ultrasound at the local hospital on May 13, 2006 showed that an intense light mass was seen in the posterior part of the uterus, measuring about 10.5×9.0 cm, and uterine fibroids were considered. Symptoms: slight abdominal distension, nasal discharge, diaphoresis, pale tongue, white fur, petechiae on the side, thin pulse. Chinese medicine diagnosis: Qi deficiency and blood stasis. The treatment is to tonify Qi and invigorate Blood, break down blood stasis and eliminate symptoms. Prescription: 25g of Radix Codonopsis Pilosulae, 10g of Radix Bupleurum, 15g of Radix Paeoniae Alba, 25g of Poria, 5g of Cinnamomum Cassiae, 10g of Peach kernel, 10g of Mudanpi, 10g of Cuttlebone, 60g of Raw Wheat Germ, 15g of Curcuma longa, 10g of Chrysanthemum, 30g of Penetrating Stone, 10g of Panax notoginseng. 1 dose daily, decoction in water, divided into 2 doses in the morning and evening, taken continuously for 1 month. Ultrasound showed no masses in the uterus and both adnexa. No recurrence since the follow-up. Gui Zhi Fu Ling Wan plus and minus for the treatment of gynecological tumors Case 3: Patient Zeng, female, 35 years old, was first seen on May 9, 2003. Complaint: No contraception but no pregnancy for 5 years after marriage. She had been treated with Shou Fetus Pill but still did not conceive and had a history of uterine fibroids. Ultrasound showed that the left posterior aspect of the uterus was seen as an intense light mass, 312.5px×275px×215px, which was considered to be a subplasma myoma. Chinese medicine diagnosis: kidney deficiency and blood stasis. The treatment is to tonify the kidney and activate blood to eliminate the symptoms and disperse the nodules. The prescription is: Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 15g, Radix Bupleurum Chinense 10g, Poria 25g, Atractylodes Macrocephala 15g, Radix Glycyrrhiza Uralensis 5g, Radix Cinnamomum Cassiae 10g, Peach kernel 15g, Mudanpi 10g, Curcuma longa 15g, Radix et Rhizoma Gastrodiae 10g, Turtle worms 15g, Penetrating stone 15g, Panax notoginseng 10g, Cyperus rotundus 15g. 1 dose daily with water decoction, divided into 2 doses in the morning and evening, for nearly 2 months. It was taken continuously for nearly 2 months. On August 7, 2003, the patient complained that she felt better after taking the medicine, her premenstrual breast pain disappeared, premenstrual abdominal distension, sleepiness, bowel movement, dark red tongue, white fur, and thin pulse. The Chinese medicine practitioner identified the same symptoms as before, and added medicine to activate blood circulation and remove blood stasis. Prescription: Radix Codonopsis pilosulae 25g, Osmanthus pilosulae 10g, Poria cocos 25g, Peach kernel 10g, Radix Paeonia lactiflora 15g, Salvia miltiorrhiza 15g, Curcuma longa 15g, Radix Panax notoginseng 10g, Dandelion 30g, Leeches 10g, Penetrating stone 15g, Panax notoginseng 10g, Turtle worms 15g. 1 dose daily, decoction in water, divided into 2 doses in the morning and evening, for 20 d. August 26, 2003, the follow-up ultrasound showed: intrauterine On August 26, 2003, the follow-up ultrasound showed that: intrauterine at 5 weeks of gestation, a strong light mass, 10.6×9.5×8.6 cm, was seen on the left posterior side of the uterus, and a subplasma myoma was considered. She continued to use Shou Fetal Pill and Gui Zhi Fu Ling Pill with addition and reduction, and delivered the fetus successfully.