Blackened intestines are considered to be colonic melioidosis. It is possible to reduce or even return to normal after removal of the causative agent.
Colonic melanosis is a lesion caused by pigmentation of the colon due to phagocytosis of macrophages with lipofuscin-like substances in the mucosa of the colon. Colonic melanosis may be related to long-term use of laxatives containing anthraquinone rings and detoxification supplements. In addition to colonic melanosis, symptoms such as constipation, diarrhea, abdominal distension, and anal swelling may occur. Colonic melanosis may also invade the colonic plexus, leading to dysfunction of the intestines as well as electrolyte disorders.
The formation of colonic melanosis is the result of prolonged melanization. After discontinuing the triggering drugs and supplements, lipofuscin can be digested and broken down by lysosomal enzymes, resulting in a reduction or even disappearance of the pigmentation. Therefore, colonic melanosis can be reduced or even returned to normal.
Establishing good bowel habits, eating more food with high dietary fiber content, drinking more water and other lifestyle habits have the potential to promote colon peristalsis and speed up recovery.