Epiphyseal closure is the disappearance of the epiphyses at the ends of the long bones. Clinically, epiphyseal closure means that the potential for growth is lost, which means that the height is fixed and there will be no further growth. Current medical technology does not have any way to treat the closure of the epiphysis. Under normal circumstances, the skeletal line should close at the age of 16 to 18 years. However, in some children with precocious puberty, the time for the skeletal line to close will be longer, and it is necessary to go to the hospital to take pictures to determine whether the skeletal line has closed or not.