The reason why people suffer from stone disease is because of the disturbance of various factors inside and outside the body, resulting in the dysregulation of the internal and external environment, the abnormal accumulation or precipitation of metabolites in the body, and the formation of stones due to abnormal mineralization in the body. Although the causes of stone disease are diverse, many factors are known to be related to the following: 1. Long-term addiction to fatty foods and other high-fat diet will increase blood lipids in the body, resulting in high saturation of cholesterol in the bile, easy to form stones; too much sweet food will promote insulin secretion, accelerating cholesterol deposition, the formation of stones. 2, do not eat breakfast, often eat late night snacks. Long-term skipping breakfast will reduce the content of bile acid, bile concentration, easy to form gallstones. And frequent nightlife, long-term eating late night sleep, the urine produced after the meal will all be stored in the urinary tract, can not be discharged in a timely manner, resulting in the urinary tract in the urine calcium content is increasing, over time, urinary stones will be formed. 3, lack of exercise, the body is too fat. Lack of exercise can easily lead to a decrease in gallbladder function and gallbladder muscle contraction, delayed bile evacuation, resulting in bile retention and stagnation, leading to cholesterol deposition into stones. Lack of exercise and eating greasy food is very likely to lead to obesity, weight more than 15% of the normal standard, the incidence of gallstones than normal people 5 times higher. 4, drinking too little water, drinking water unclean. Drinking too little water to reduce the volume of urine, resulting in urine concentration, urine turbidity and increased urine salt precipitation, increased urine salt crystals, prompting the formation of stones. Usually drink unclean water is also very easy to induce urinary stones. 5, long-term alcohol abuse, unhealthy diet. Often drink a lot of alcohol, drink strong tea, etc. will lead to increased urinary calcium, uric acid levels, increasing the incidence of urinary stones. At the same time, often eat seafood when drinking beer and other bad eating habits will make the human blood uric acid content increased, out of balance, resulting in uric acid can not be discharged in a timely manner, in the form of sodium salt deposited, thus forming stones. 6, blind calcium supplementation, mental disorders. When the human body liver, kidney, gallbladder and other organs of metabolic dysfunction or sex hormone decline, will lead to a false calcium deficiency, at this time, if blindly calcium supplementation, will easily lead to stone disease; if a person long-term mental tension, depression, can make the internal organs disorder, affecting the liver and gallbladder Shu Shu function, resulting in poor bile flow, bile stagnation in the gallbladder, bile components disproportion, prompting stone generation. 7, other diseases. Metabolic disorders caused by some diseases can also cause stone disease, such as: hyperparathyroidism, cortisol, bone marrow disease and other diseases can cause bone decalcification and high blood calcium and high calcium urinary stones; large intestinal resection, intestinal anastomosis short circuit and chronic gastrointestinal diseases can cause excessive absorption of oxalic acid and high oxalic acid urinary stones; gout patients with purine metabolism to form gouty stones; malignant tumors, leukemia patients due to unlimited malignant cell In patients with malignant tumors and leukemia, the purine metabolism is enhanced due to unlimited malignant cell proliferation and destruction, resulting in a significant increase in uric acid in the urine and the formation of stones; intestinal roundworms enter the bile ducts, causing bile duct inflammation, ulceration, and eventually scarring, resulting in bile duct narrowing and poor circulation of bile, and even stagnation, gradually forming stones in the bile ducts.