Blood phosphorus control in dialysis patients is a serious problem, and many patients pay insufficient attention to bring about significant hyperphosphatemia, which leads to a series of complications. 1, the generation of hyperphosphatemia Under normal circumstances, people through the diet for phosphorus intake, by the kidneys to excrete it. For dialysis patients with renal insufficiency, especially in stage 5 chronic kidney disease, on the one hand, the excretory function of the kidneys is reduced or lost, and the phosphorus ingested in the diet cannot be excreted normally, on the other hand, these patients may receive less dietary education related to dialysis, or they do not pay attention to it, and consume too much phosphorus-rich food, resulting in the accumulation of phosphorus in the body and hyperphosphatemia. 2, the dangers of hyperphosphatemia Hyperphosphatemia itself does not produce any symptoms, but because it can lead to a series of complications and cause a high degree of concern. First, when the body’s blood phosphorus is too high will appear phosphorus from the intestinal compensatory elimination and combined with calcium, limiting the body’s calcium absorption, coupled with renal abnormalities in patients with impaired vitamin D production, reducing the absorption of calcium, these factors together make hemodialysis patients more likely to have lower blood calcium. Secondly, high blood phosphorus and low blood calcium can stimulate the parathyroid glands and cause secondary hyperparathyroidism, which can eventually lead to a variety of renal bone diseases, including fibrocystic osteitis, osteogenesis imperfecta, osteochondrosis and osteoporosis. So pay attention to the dynamic changes in blood phosphorus, to be timely and correct treatment, is a topic that we should not ignore. 3, the prevention and treatment of hyperphosphatemia Through the analysis of the occurrence of hyperphosphatemia, we understand that excessive intake of phosphorus is the source of all the evils of hyperphosphatemia, so to prevent and control hyperphosphatemia: first, the intake of phosphorus should be controlled. Protein is the main food that contains phosphorus, but protein is divided into high-quality protein and non-quality protein. Controlling the intake of phosphorus-containing foods does not mean restricting protein intake all together; hemodialysis patients should eat foods rich in high-quality protein appropriately, otherwise excessive restriction of intake can also cause malnutrition. Second, adequate dialysis can help control hyperphosphatemia. Finally, for patients for whom the above measures are still ineffective, appropriate phosphorus-binding agents can be selected according to the patient’s indicators. With the use of phosphorus binding agents, phosphorus is combined with dietary phosphorus in the gastrointestinal tract after oral administration to form substances that are difficult to be absorbed and then excreted through the feces, thus reducing the absorption of phosphorus in the intestine. There are some new phosphorus-binding agents in the clinic that have achieved good results in correcting blood phosphorus, but they have not been widely used because they are all expensive. These drugs can be recommended for the treatment of patients who are financially well off and whose blood phosphorus is difficult to correct.