1, genetic factors: the occurrence of scoliosis and genetics is directly linked to a number of studies have shown that the occurrence of scoliosis genetic factors. Population studies have shown a family history of the population, the incidence of idiopathic scoliosis is higher than the general population. 2, hormone theory: According to experts, growth hormone is also caused by scoliosis, there are individual reports of rapid progression of scoliosis caused by taking growth hormone. Interestingly, melatonin and growth hormone are secreted in a similar way, but the opposite day and night. 3, biological reasons: The occurrence of scoliosis and human growth is also related, especially the time of rapid growth during puberty. Different growth rates on the left and right sides of the spine produce an asymmetric biomechanical load. 4, tissue abnormality theory: Scoliosis is likely due to abnormalities in the patient patient’s tissues. Several theories propose that abnormalities in the structures associated with the spine (muscles, bone, ligaments, and/or discs) may lead to scoliosis. This theory is based on the observation that conditions such as Marfon syndrome (protofibrinopathy), Duchenne muscular dystrophy (myopathy), and osteofibrous dysplasia all complicate scoliosis.