On Feb. 8, at 6:00 p.m., a round of applause came from the catheterization room of the Institute of Cardiology: a patient with severe angina pectoris who was completely occluded from the opening of the anterior descending artery and had failed to open it after several interventional procedures in outside hospitals was operated by Director Wang Yu, who went through the right coronary vessel and the tiny left collateral vessel and reached the distal end of the occluded left coronary vessel retrogradely and opened it retrogradely. The patient’s severe angina symptoms were completely relieved with the application of only one stent, which opened the huge anterior descending vessel that had been occluded for more than 5 years. This is the first case of minimally invasive, successful retrograde microvascular opening of an occluded heart vessel via the contralateral side. Chronic total occlusive lesions are currently the last “bastion” in the field of cardiac revascularization that has not been completely conquered internationally. The basic principle of the reverse technique is to reverse the track through the contralateral vessels and then completely open the heart vessels that have been occluded for a long time. At present, only a few large cardiac centers in China are able to perform it, and the number of cases is very small. Its significant advantages are: tiny incision, little patient pain and fast recovery. The opened blood vessel can be kept open for a long time with the application of drug stents, which can completely relieve the patient from severe myocardial ischemia. It is especially suitable for patients of advanced age, with multiple organ dysfunction, or very young patients with occluded coronary artery. This technique is currently the most complex and technically demanding technique for opening occluded heart vessels internationally. The team led by Director Wang Yu of the Institute of Geriatric Cardiovascular Disease performed this complex cardiac intervention for the first time independently and successfully in one visit, after observing several surgeries by foreign experts, requesting lectures from renowned experts both at home and abroad, and actively and carefully preparing the patient and the catheterization laboratory for the procedure. This makes the minimally invasive interventional treatment of complex and advanced coronary heart disease reach the international advanced level. In the past year, the Institute of Geriatric Cardiovascular Diseases, under the leadership of Academician Wang, who continues to work despite his illness, and inspired by the spirit of the master, has been following the international academic frontier, actively carrying out new technologies and new businesses, and striving to relieve the pain of patients with complex, elderly and high-risk coronary heart disease. At present, the Heart Research Institute is rapidly reaching the advanced level in China in terms of emergency treatment of acute myocardial infarction, minimally invasive diagnosis and treatment of complex, high-risk and high-risk coronary heart diseases, complex coronary heart diseases such as left main trunk lesions, coronary bifurcation lesions, highly calcified-sclerotic stenosis lesions, chronic occlusive lesions and other interventional diagnosis and treatment techniques. With the recently performed spin-grinding technique for highly calcified coronary vessels and the successful reverse opening technique for chronically occluded heart vessels, the Institute has mastered all the most technically challenging treatments for coronary heart disease that can be performed internationally. It brings the latest minimally invasive treatment technology for the majority of difficult coronary heart patients. He is a well-known interventional cardiologist in China; he has deep attainments in basic and clinical research on prevention, diagnosis and treatment of coronary heart disease; especially for the minimally invasive interventional diagnosis and treatment of complex and high-risk coronary artery disease, advanced coronary heart disease, multi-organ diseases with respiratory and renal dysfunction, etc., he is at the leading level in China and internationally. He has successfully completed more than 11,000 cases of interventional treatment for complex coronary artery diseases; completed emergency access treatment and comprehensive emergency treatment for nearly 1,000 patients with acute myocardial infarction and acute coronary syndrome, with a rescue success rate of more than 98%. He is proficient in: coronary left main lesions, chronic occlusive lesions, high calcification vascular spin mill treatment techniques, interventional treatment of high-risk and complex coronary lesions such as advanced coronary artery disease (the highest age is 95 years old), acute myocardial infarction and acute coronary syndrome. He has also successfully completed stent recanalization and reverse recanalization of renal artery, iliac artery and subclavian artery stenosis and occlusion in more than 800 cases. From 2004 to 2005, he was a senior visiting scholar of the Ministry of National Education at the Heart Center of the University of Heidelberg, Germany, and was granted a temporary medical license to practice medicine in the EU/Germany. He has published more than 60 research papers in domestic and international journals, and has received 3 National Natural Science Foundation of China (NSFC), National 863 Project and several Beijing Premiere Foundation projects. He has received 3 awards of the 2nd and 3rd class of the Army Science and Technology Progress Award. He has organized and participated in a number of international and national projects, as well as the “Ninth Five-Year Plan” and “Tenth Five-Year Plan” key projects of the whole army; he has trained 7 master students and 8 doctoral students.