Dry and cracked lips in spring can be treated in general if it is due to weather factors as well as bad habits. If the dry and cracked corners of the mouth are caused by infectious xerostomia, an antifungal infection medication (ketoconazole) can be used. If the lips are dry and cracked due to contact keratitis, anti-allergy drugs (loratadine) can be used. 1. Weather factors and bad habits: avoid hot and cold lip stimulation and sun exposure, keep lips moist and clean, apply lip balm, pay attention to oral hygiene, maintain a good mood, pay attention to a balanced diet. 2. Infectious keratitis: need to eliminate the causes in time, improve the bad habit of licking lips, but also need to target the pathogenic microorganisms for anti-infection treatment. If it is a fungal infection, you can use ketoconazole, fluconazole. 3. Contact keratitis: need to remove allergens as soon as possible, the timely use of anti-allergy drugs, such as loratadine, chlorpheniramine. The use of drugs need to follow the doctor’s instructions, not blindly. There are many reasons for dry and cracked lips in spring, if there is no recovery for a long time, it may be caused by pathological factors, and it is recommended to go to the hospital for examination and treatment.