Barbara Baier from the Department of Cardiothoracic Surgery, Fachkrankenhaus Coswig Hospital, Germany, published in the 2015 issue of the cardiovascular and thoracic journal Interactive CardioVascular and Thoracic Surgery a study on renal clear Cell carcinoma patients who underwent extended laser resection of metastases as well as systematic lymph node dissection were studied for survival outcomes. This was done to assess the efficacy and value of laser resection for patients with different numbers of metastases. From 1996 to 2012, 237 patients (150 males and 87 females) with pulmonary metastatic renal clear cell carcinoma underwent radical laser resection of pulmonary metastases with a total of 2996 metastases (minimum of 1 and maximum of 110 metastases per case) were studied. Overall survival was assessed in all 237 patients and in each subgroup using KaplanCMeier analysis, and multifactorial analysis of prognostic factors was performed using Cox regression models. Results The 5-year overall survival rate for 208 patients (88%) who underwent complete laser resection of metastases was 54%, with a median overall survival rate of 69 months, significantly higher than the corresponding 7% and 19 months for patients who underwent incomplete resection, respectively ( log-rank P < 0.00001). On average, 13 metastases were resected per patient. The number of metastases removed was 1, 2-5, 6-9, 10-29, and 30-110, corresponding to 5-year survival rates of 62%, 59%, 60%, 43%, and 40%, respectively. multivariate Cox regression analysis of the 237 patient data showed that the completeness of resection and the number of metastases were independent influences. This study suggests that if complete resection is achieved, laser resection can achieve substantial long-term survival after removal of a high number of metastases, comparable to the survival rates reported in other relevant studies. This tissue preservation technique allows for repeat resections to prevent recurrence.