Retinopathy of prematurity, formerly known as posterior lens fibrous hyperplasia, was first reported by Terry in 1942, when white fibrous tissue was found behind the lens in premature infants and named after it. Studies have shown that the disease is closely related to prematurity, low birth weight, and high oxygen intake, and is caused by retinal neovascularization and fibrous tissue proliferation in premature infants whose retinal vasculature is not fully developed. Posterior lens fibrous hyperplasia is a late scarring change of severe ROP, which was officially named retinopathy of prematurity by the World Academy of Ophthalmology in 1984. Prevention (dietary care) I. Feeding 1. advocate early feeding, low weight or poor general condition, such as those who have had cyanosis, respiratory distress or surgical delivery, can be appropriately delayed feeding, intravenous rehydration. Effect: To shorten the time of physiological weight loss or reduce the degree, the occurrence of hypoglycemia rate is reduced, and the concentration of blood bilirubin is relatively reduced. Generally 6-12 hours after birth to start feeding sugar water, 24 hours to start breastfeeding. 2.Feeding method: For heavier birth weight and good sucking reflex, direct nursing can be used, and vice versa with a drip tube or gastric tube feeding. 3, the maximum intake: (1) within 10 days of birth: daily nursing amount (ml) = (baby born full days + 10) × weight (grams / 100) (2) after 10 days of birth: daily nursing amount (ml) = 1/5-1/4 body weight (grams) (3) premature babies can not eat all, the remaining part can be supplemented by intravenous. 4.Feeding interval: (1) Those who weigh less than 1000 grams: feed once every hour. (2) Weight 1001-1500 grams: feed every 1.5 hours. (3) weight 1501-2000 grams: every 2 hours feeding. (4) weight 2001-2500 grams, once every 3 hours. Second, the nutritional requirements 1, calories: 110-150 kcal per kg of body weight per day. It is appropriate to start with a slightly lower supply, and gradually increase according to the situation. 2.Amino acid: Premature babies lack the relevant converting enzyme and cannot convert methionine into cystine and phenylalanine into tyrosine, so cystine and tyrosine become essential amino acids and must be taken from food. 3.Protein: The protein intake of preterm infants is higher than that of normal infants. 4.Vitamin: Premature infants lack vitamin E and are prone to hemolytic anemia. Premature infants do not absorb fat as well as mature infants, and may lack fat-soluble vitamins and other nutrients. 5.Inorganic salt: more than mature babies need.