Hypospadias is one of the most common congenital malformations in men, mainly manifesting as a downward curvature of the penis, abnormal position of the urethral orifice and abnormal distribution of the foreskin. The success rate of the first stage of surgery is about 80% or more, so what are the main post-operative comorbidities of hypospadias, mainly according to the recent, medium and long-term to distinguish, the recent comorbidities mainly include, post-operative local bleeding, local infection, urinary tract infection, wound dehiscence, urethral skin fistula and so on. The mid- and long-term comorbidities are surgery-related comorbidities that occur after three months after surgery, including urethral stricture, urethral diverticulum (dilatation), erectile pain, ejaculatory disorders, etc. Among them, urethral skin fistula occurs slightly more often, which can wait for observation or be repaired locally about one year after surgery. The management of urethral strictures is based on urethral dilation. Urethral diverticulum requires local surgical reconstruction of the urethra if it interferes with urination. Complications of hypospadias can be repaired by local management or reoperation.