There are many reasons for repeated acne around the mouth, including the following: 1, folliculitis: the most common, caused by Staphylococcus aureus infection; 2, herpes simplex: because of viral infection; 3, dermatitis. It is mainly due to folliculitis and herpes simplex. If it is folliculitis, it may be due to eating spicy and stimulating food or mutton or seafood, and the face is prone to acne around the mouth. If it is herpes simplex, it may also be related to diet, such as fish and shrimp and other seafood, spicy and stimulating food. Others are tired, fatigued, poorly rested or immune system can grow acne. Folliculitis can be treated with topical anti-inflammatory creams, like the common Bactrim, fusidic acid ointment, and erythromycin eye ointment. If it is a herpes simplex virus infection, you can use topical acyclovir ointment and take oral antiviral drugs such as milk famciclovir and valacyclovir.