Callus on the hand is the clinical callus, and consider and long time friction, pressure related. It is recommended to pay attention to strengthen moisturizing, if necessary, through the drug or surgical grinding treatment to remove. 1. Enhance moisturizing: it is recommended to pay attention to the care of the hands, often engaged in hand work, you can wear gloves, but also pay attention to the hands of moisturizing and hydrating skin care, can help improve. 2. medication: callus on the hand is thicker, every night with hot water soaking hands, can be combined with the doctor’s advice to give urea ointment, salicylic acid ointment mixed topical application. Persistent use, calluses on the hands can gradually fall off. 3. Surgical grinding: calluses on the hands for a long time can not get better, you can go to the hospital dermatology consultation, if necessary, surgical grinding, prompting the thick layer of keratin off, but also to promote drug absorption. Calluses on the hands and long-term friction related, it is recommended to pay attention to the care of the hands, if necessary, hospital visits, under the guidance of doctors for treatment, do not self-medication.