A normal blood ketone body value is below 1.0 mg/dL, suggesting that the body is in energy metabolic balance. The production of ketone bodies is due to a lack of energy turning to the breakdown of fat, which leads to the production of metabolic waste on the way to the breakdown of fat metabolism. Excessive accumulation of ketone bodies can easily lead to metabolic acidosis, also known as ketoacidosis. When blood ketone bodies increase, there are usually the following reasons: 1. High blood sugar: insulin cannot bind to insulin receptors on cells, which will cause plasma glucose not to enter the cells to be used, resulting in impaired sugar metabolism in the human body and elevated blood ketone body levels. At this time, insulin supplementation is needed to help accelerate the utilization of blood glucose and reduce the generation of ketone bodies; 2. Loss of body fluids: If patients have gastrointestinal diseases, long-term vomiting, diarrhea or deliberate dieting to lose weight and other symptoms, the loss of excessive human blood ketone bodies due to high-intensity physical exercise causes the rise of starvation ketosis. Appropriate energy supplementation can be carried out to help the blood ketone body gradually return to normal; 3, kidney disease: it will lead to the blood ketone body can not be well discharged, appearing high state, when necessary, but also combined with blood gas analysis, to understand whether the blood ketone body level is elevated when the human body has metabolic acidosis.