Elevated postprandial blood glucose is no less harmful to patients than fasting blood glucose and affects patients’ blood vessels and nerves because blood glucose variability increases significantly after elevated postprandial blood glucose. Increased blood glucose variability increases blood glucose volatility and can damage vascular endothelial and microvascular endothelial cells. Recent studies have found that the incidence of diabetic nephropathy and diabetic retinopathy increases significantly with significantly higher postprandial glucose. At the same time, the incidence of macroangiopathy and diabetic patients with combined cardiovascular and cerebrovascular diseases will increase significantly. Therefore, the clinic should not only pay attention to fasting blood glucose, but also pay more attention to postprandial blood glucose, so as to reduce postprandial blood glucose and reduce the rate of glucose variability, which is more conducive to reducing chronic complications and neuropathy.