The effect of electrode placement on cognitive function during ECT treatment, current studies on electrode placement have focused on the comparison between bitemporal, right unilateral, bifrontal and bilateral frontotemporal, Squire et al. reported that right unilateral ECT (i.e., non-dominant hemisphere ECT) had the least effect on cognitive function and caused less amnesia and disorientation than other modalities, but bitemporal ECT was more effective than right unilateral ECT. Traditionally, we believe that both TECT treatment and MECT treatment have affected intelligence and memory adverse effects, and mostly prefer MECT treatment to TECT treatment for less recent memory impairment. The effect of MECT treatment on patients’ memory is temporary and can be restored to the pre-morbid level 2 weeks after termination of treatment. In contrast, the effect of TECT treatment on memory lasts for more than 2 weeks. Memory function and abstract thinking ability are important components of cognitive function, and cognitive dysfunction in schizophrenia can be improved or even restored to a large extent by effective treatment. MECT treatment may not be detrimental to memory function and abstract thinking ability in schizophrenia, and may even improve these impairments by improving symptoms. The study by Li Champion et al. also did not find any significant impairment of cognitive function in elderly depressed patients by MECT. Many scholars have suggested that the combination of antipsychotics should be avoided before ECT treatment to reduce the impairment of cognitive function. Xie et al. concluded that the combination of low potency antipsychotics before ECT treatment may lead to shock hypotension, because the hypotensive effect of low potency antipsychotics can be enhanced by ECT. Clozapine is likely to cause prolonged respiratory time, so it should be avoided or used sparingly in treatment to avoid prolonged confusion and increased cognitive impairment after the patient wakes up from a convulsion. In contrast, Chen Zhengping believes that: under conventional dose conditions, all kinds of psychotropic drugs (including antipsychotics, antidepressants, benzodiazepines, lithium salts, antiepileptic drugs) have no significant effect on the effect of MECT seizures, and it is not necessary to consider stopping or reducing drugs before treatment, benzodiazepines have a certain relationship with the control of treatment power, therefore, in the operation of electroconvulsive therapy for the use of larger doses of benzodiazepines Therefore, during electroconvulsive therapy, a larger dose of benzodiazepines can be considered for patients.