Chronic viral hepatitis is classified as mild, moderate or severe. Moderate is generally based on transaminases greater than 5 times normal and less than 10 times normal, total bilirubin greater than 3 times normal and less than 5 times normal, albumin greater than 32 g/L; HBV-DAN positive; histopathology characterized by the presence of bridging necrosis, the lesions must be active, but clinical manifestations can have a wide range. The disease progresses, typically with obvious symptoms of liver disease: weakness, poor appetite, abdominal distension, loose stools, etc.; the liver is enlarged and tough, the spleen is also often enlarged, and there may be a liver disease face, xanthogranuloma, spider nevus, liver palms, etc. First of all, liver preservation and enzyme-lowering treatment should be carried out. When transaminases are reduced to less than 200 U/L and clinical symptoms improve, further testing of A IV should be carried out to exclude thyroid disease, and anti-nuclear antibody, anti-mitochondrial antibody, anti-smooth muscle antibody, anti-hepatic and renal microsomal antibody should be detected to exclude autoimmune diseases. After excluding serious heart disease, kidney disease, epilepsy, diabetes, pregnancy, psoriasis, alcoholism, uncontrolled hypertension and other diseases, especially for young people with fertility requirements, interferon can be given intramuscularly for antiviral treatment to control the development of the disease, and the efficacy is certain with a certain course of treatment. After achieving a complete response, pregnancy and children can be born six months after stopping the drug. The nucleoside analogue antiviral drugs, although simple to take, but the course of treatment is not fixed, and none of the clinical pregnancy trials, do not know whether there is no effect on the fetus and sperm, there is no evidence-based medical evidence.