Kidney stone with hydronephrosis during pregnancy can be treated conservatively, elective surgery after delivery, nephrolithotomy and fistula according to different clinical manifestations. 1. Without any symptoms or mild symptoms: If the stone is small and the infection is not serious, you can decide how to treat it conservatively according to the presence or absence of symptoms. If you do not have any pain symptoms, you can drink more water and urinate more often in your daily life and have regular checkups. If the symptoms are mild, you can wait until after delivery to deal with the stone at a later date. 2. With obvious pain: The biggest complication of kidney stones with fluid accumulation is kidney function damage as well as serious infection. If the stone is large and completely blocks the ureter, the hydronephrosis seriously affects the kidney function, or is accompanied by obvious pain, minimally invasive lithotripsy can be considered after evaluation by obstetrician-gynecologists and anesthesiologists, and nephrostomy can be considered if necessary. In case of kidney stones with hydronephrosis during pregnancy, it is recommended to seek medical advice from obstetricians, gynecologists, urologists and anesthesiologists, and choose the appropriate treatment plan according to the severity of the disease to avoid delay.