Generically known as Gliclazide Extended-Release Tablets, Damicam can be used in combination with Metformin.Gliclazide Extended-Release Tablets are usually taken with breakfast. The tablets are swallowed whole and should not be chewed or crushed. Metformin is usually taken with or after meals, but you need to consult your specialist on how to take it. 1. Gliclazide extended-release tablets: belonging to the sulfonylurea hypoglycemic drugs, by promoting the release of insulin, thereby reducing blood sugar, mainly for patients with type 2 diabetes mellitus who have unsatisfactory glycemic control by diet and exercise alone. The main adverse reaction of this product is hypoglycemia, which is prohibited for patients with type 1 diabetes and those who are allergic to the ingredients of this drug. 2. Metformin: It belongs to the class of biguanide glucose-lowering drugs, through reducing the output of hepatic glucose and improving peripheral insulin resistance, in order to achieve the purpose of lowering glucose, which is mainly applicable to patients with type 2 diabetes mellitus. This product may have adverse reactions such as nausea, vomiting, diarrhea, etc. It is prohibited for people with renal insufficiency, serious infection and shock. Gliclazide extended-release tablets and metformin are prescription drugs, need to be used under the guidance of a doctor, not blindly used together.