In one typical case, he had a diabetic lower extremity vasculopathy combined with dry gangrene, but he kept putting vascularization in the first place and kept wondering what drugs would work well, while neglecting the treatment of the inflammatory necrotic wound, thinking that he had heard that the wound would fall off on its own when it “matured” and therefore did not need special treatment. This is a misconception! This is a misconception, I tell you! First of all, let’s answer this patient’s question: What is the best medicine for lower extremity arterial occlusion? The medication should definitely be symptomatic, if not the effect is definitely not good. At present, antiplatelet drugs, statins, angiotensin converting enzyme inhibitors (ACEI) and vasodilator drugs can be used to improve the motor function of the lower limbs, and pain medication can be used to relieve pain when there is severe limb ischemia. Another thing to note from life is that lesions are closely related to age, smoking, duration of diabetes, blood sugar stability, combined cardiovascular and cerebrovascular diseases, high systolic blood pressure, previous history of foot gangrene, high cholesterol, etc., which should be combined with medications and diet regulation, exercise, etc., for comprehensive management and treatment in life. Then, let’s talk about where the misconceptions lie: it is the neglect of the management and treatment of inflammatory trauma. Although for most patients with dry gangrene, wound infection is not the most typical and prominent feature, we can not just wait, although in Chinese medicine it is also called “deglutition”. This so-called “deglutition” should not wait for it to fall off on its own, but should be cleaned surgically and artificially. In some patients, the ischemia is not severe, but the inflammatory toxins can still be transported through the blood to other parts of the body, especially in the mixed gangrene type, which is both ischemic and infected, and the chance of sepsis is still high. Therefore, in patients with lower extremity arteriopathy combined with diabetic foot like this, the treatment plan must not be formulated in favor of one point, but should be formulated with a targeted treatment plan for all the patient’s problems, comprehensive treatment, and comprehensive treatment in order to avoid serious harm to the patient.