The diabetic foot, also known as the diabetic foot, is the result of diabetic lower extremity vascular disease. Amputations due to diabetic foot are 5 to 10 times more common in diabetic patients than in non-diabetic patients, and diabetic foot is the leading cause of limb disability in diabetic patients. The typical diabetic foot is a foot with insufficient blood supply due to vascular disease, sensory loss due to neuropathy, and infection in diabetic patients. Similar pathological changes can actually occur in the upper extremities, face and trunk, although the incidence of diabetic foot is significantly higher than in other areas. The main symptoms of diabetic foot are lower extremity pain and skin ulcers, which can range from mild to severe, including intermittent claudication, lower extremity rest pain, and foot gangrene. Early physical examination of the lesion can reveal signs of insufficient blood supply to the lower extremities, such as pale skin on the foot when the lower extremity is elevated, purplish red when the lower extremity is lowered, cold feet, and weakened or even absent dorsal foot artery pulsations. The so-called intermittent claudication is that patients sometimes walk and suddenly have pain in the lower extremities, so that they walk with a limp or simply cannot walk, which is an early manifestation of lower extremity ischemia. Rest pain is the result of further development of lower limb vascular disease, not only the pain caused by insufficient blood supply to the lower limb when walking, but also the pain of the lower limb due to ischemia when resting, which can make the patient sleepless at night when serious. With further development of the disease, gangrene can appear on the lower extremities, especially on the feet, and the wounds may not heal for a long time, and the skin may even open up and crack, and the toes may fall off one by one, making the situation unbearable. Gangrene can be classified as wet, dry or mixed, depending on the local manifestation of the gangrene. Severe cases of gangrene will result in disability due to amputation. The treatment of diabetic foot should also focus on prevention, preferably not, and should be treated early after getting it, so as not to think that “it doesn’t hurt, it’s fine” and delay the disease, which eventually leads to amputation. Prevention and treatment means include: (1) strict control of diabetes, including hyperglycemia, hypertension, dyslipidemia and high blood viscosity control. The blood sugar can be controlled by long-term use of pancreatic precipitin regulator Etanercept, long-term use of vasoactive drugs and enteric aspirin, compound salvia tablets, golden pulse capsule and other drugs to reduce blood viscosity; (2) pay attention to foot hygiene. To protect the clean and dry feet, often soak feet with warm water, but avoid foot burns, and use vegetable oil to massage after washing. Avoid wearing tight, ill-fitting shoes, and pay attention to the removal of foreign objects in shoes to avoid abrasion of the skin. Pay attention to trimming toenails, not too short and too bald. Active treatment should be given to corns and any minor foot injury or infection to avoid the formation of ulcers or gangrene; (3) improve circulation in the lower limbs. Pay attention to foot warmth and quit smoking to ensure adequate blood supply to the lower extremities. Here again, smoking can further constrict blood vessels, which is an important cause of lower limb necrosis, so for the sake of your feet, you must quit smoking, and the practice of “smoking without feet” is not advisable; (4) treatment of diabetic foot. Once the diagnosis of diabetic foot is established, it must be treated immediately and actively to avoid the development of the disease, causing disability or death. Treatment measures include scopolamine, 654-2 and other blood circulation drugs, antibiotics to control infection, foot replacement and surgical treatment. Vascular bypass surgery can be effective in improving circulation to the lower extremities. Amputation should be performed if the gangrene of the lower extremity is severe and conservative treatment is ineffective.