Muscle soreness is an adverse reaction that occurs after taking Atorvastatin Calcium, and there is no clear indication of how long it will take to develop. Sometimes muscle soreness occurs within 1 week of taking the drug, but sometimes it occurs only after taking the drug for several years, which varies from person to person. Atorvastatin Calcium has the efficacy of lowering blood lipids and stabilizing plaque, and can be used clinically for the treatment of hyperlipidemia, and can also be taken by people with coronary artery disease and diabetes mellitus combined with hypercholesterolemia in order to reduce the risk of stroke and angina pectoris. Pregnant women, lactating women and those who are allergic to the drug composition of atorvastatin calcium are prohibited from taking it. Atorvastatin Calcium should be used with caution in allergic individuals. Adverse reactions such as rhabdomyolysis, myopathy, skeletal muscle pain, joint swelling, and liver enzyme abnormalities may occur with current administration of Atorvastatin Calcium. Clinically, taking Atorvastatin Calcium is able to cause adverse reactions such as muscle aches and pains, but the time of occurrence of adverse reactions cannot be generalized, as each person has a different constitution and tolerates the drug differently. Sometimes it occurs about 1 week after taking the drug, and sometimes it occurs after several years of taking the drug. The medication should be applied rationally according to the doctor’s instructions, and if there is any discomfort, consult the doctor in time.