Elevated blood creatinine indicates renal insufficiency. In the early stage of elevated blood creatinine, there may not be any symptoms, which are found through physical examination. As time goes by, patients with elevated blood creatinine may feel general weakness, back pain and discomfort, and also experience digestive symptoms such as loss of appetite, nausea and vomiting, and may mistakenly think they have gastritis and go to the gastroenterology department. If the blood creatinine rises further and reaches a more serious level, a series of complications may occur, such as: 1. hypertension, which may be manifested as dizziness and headache; 2. edema, which may lead to generalized edema in severe cases; 3. heart failure. There will be chest tightness and panic after activity, and there will also be a decrease in platelets, petechiae and petechiae all over the body, and other patients will have anemia and general discomfort.