Giving birth to a healthy baby is the common wish of all young couples in the world, and it is also the most concerned issue for pregnant women during pregnancy. Quite a number of female patients with hepatitis B who have not yet married have one more worry, worrying that marriage and childbirth will aggravate the disease, and at the same time, they are afraid of transmitting the hepatitis B virus to their future babies, and a lot of young female patients with hepatitis B are worried about this. If hepatitis B patients do not correctly grasp the timing and method of marriage and childbirth, it will indeed bring adverse consequences. However, as long as young women with hepatitis B take proper precautions before and after pregnancy, the transmission of the hepatitis B virus from the mother to the baby can be completely blocked. When hepatitis B patients with active disease get married, excessive sexual life will lead to increased burden on the liver and make liver inflammatory activity more serious, and if women with active liver inflammation get pregnant, it will easily lead to increased burden on the pregnant woman’s liver, necrosis of liver cells, and evolve into severe hepatitis. If the babies born to pregnant women with hepatitis B are not vaccinated against hepatitis B in time, almost all of them will become new “little hepatitis B”, and may develop into chronic hepatitis B virus carriers, or even cirrhosis or liver cancer in the future. Therefore, many women with hepatitis B virus are afraid to get pregnant and have children. Hepatitis B mother-to-child transmission is not 100% The medical phenomenon that the mother has hepatitis B and passes it on to the next generation is called “mother-to-child transmission”. The so-called “mother-to-child transmission” refers to pregnant women who have hepatitis B or carry the hepatitis B virus in their bodies, and transmit the hepatitis B virus to their fetuses or newborns during pregnancy or delivery, which is the most important and threatening way of transmission of hepatitis B. The most important and threatening way of transmission of hepatitis B is that pregnant women who carry the hepatitis B virus and are not infected with the hepatitis B virus are not infected with the virus. If a pregnant woman carries hepatitis B virus, not 100% of the hepatitis B virus will be transmitted to the fetus or newborn, whether it will lead to hepatitis B virus infection of the fetus or newborn depends on the replication degree of hepatitis B virus carried by the pregnant woman and the genetic defect of the mother. If a pregnant woman is hepatitis B “triple positive” (hepatitis B e antigen positive) and her hepatitis B DNA is also positive, the chance of her newborn being infected with the hepatitis B virus is as high as 90%; however, if the pregnant woman’s hepatitis B e antigen is negative and her hepatitis B DNA is negative, the chance of her being infected is only about 30%. This is why some people in families with a tendency for hepatitis B to run in clusters get hepatitis B, while others don’t. The most important way to stop mother-to-child transmission is to prevent the spread of hepatitis B from mother to child. The most important way to stop mother-to-child transmission is to vaccinate babies against hepatitis B immediately after birth, and it is more effective if the vaccine is combined with hepatitis B immunoglobulin, which is more than 90% effective in stopping mother-to-child transmission of hepatitis B virus. At the same time, we should also take corresponding countermeasures, pay attention to the prenatal, during the birth process and after the birth of the child all kinds of prevention. Hepatitis B patients can get married and give birth. First, if the woman is hepatitis B, immediately after the birth of the baby, the first injection of a hepatitis B immunoglobulin, at the same time or after one week, according to the 0th, 1th and 6th month immunization program (the first shot of hepatitis B vaccine after the birth of the first shot of hepatitis B vaccine after a month, the second shot of hepatitis B vaccine after 6 months, the third shot of hepatitis B vaccine after 6 months), respectively, in the baby’s forearm, the deltoid muscle subcutaneous or intramuscular hepatitis B vaccine, 10 micrograms each time. 10 micrograms each time. The combined immunization of hepatitis B vaccine and hepatitis B immune protein immediately after the birth of newborns can achieve 95-97% blocking effect. Secondly, at present, there is no definite report on giving immunoglobulin to pregnant women to prevent mother-to-child transmission, and there is no high-level evidence-based medical evidence. There is no high level of evidence-based medical evidence. The current WHO and China’s Ministry of Health and prevention and treatment guidelines have not formed this recommendation. The theoretical basis for using high-priced immunoglobulin for pregnant women is to reduce HBV-DNA in pregnant women, which is actually difficult to achieve. One study found that after three injections of 200 IU immunoglobulin in pregnant women, no immunoglobulin could be detected in the serum of pregnant women and newborns. In addition, no change was found in HBVDNA levels in 17 pregnant women examined before and after immunoglobulin injections. So from these evidences, the use of hepatitis B immunoglobulin to block mother-to-child transmission has not been well-founded. It is best to check for e antigen e antibody before marriage The partners of a person with hepatitis B need to be actively protected. Men and women, if one party is a carrier of hepatitis B surface antigen, then it is best to check e antigen and e antibody before marriage, if the carrier e antigen positive (“big three sun”), indicating that the infectiousness of the healthy party is even more necessary to do the hepatitis B seropathology (“two to half “If the surface antibody of hepatitis B is positive and the others are negative, it indicates that immunity against hepatitis B virus has been produced and it is not easy to be infected, so it is not necessary to take the vaccine; if the hepatitis B “two-to-half” test, the indicators are negative, it indicates that there is no infection of hepatitis B virus, and there is a lack of immunity against hepatitis B virus, at this time, the healthy party needs to take the vaccine. If the test of Hepatitis B “two-to-half” is negative, all the indexes show that they have not been infected by Hepatitis B virus and lack immunity to Hepatitis B virus, the healthy party should take Hepatitis B vaccine according to the program of “0, 1, 6”, and then get married after generating surface antibody. If the test result of the subject of hepatitis B patient is positive for core antibody and/or e antibody, it means that he/she has been infected with hepatitis B virus in the past, but now he/she is fine, and he/she can take the vaccine. The body will be prompted to produce hepatitis B surface antibodies. If the carrier’s e antibody is positive (“small triple positive”), it indicates that the virus replication has been weakened, the infectiousness has decreased, or it is a variant of the e antigen, and the healthy party should also get married after the hepatitis B vaccination under the guidance of the physician. After the injection of hepatitis B vaccine, generally can maintain immunity for more than 3 – 5 years, can be repeated after 3 or 5 years, a considerable part of the people can benefit from a hepatitis B vaccination for life. Do not use drugs that are toxic to the liver Generally speaking, patients with hepatitis B can get pregnant if their liver function is normal for a long time and there is no obvious discomfort in their body. Once pregnant, pregnant women should pay attention to the following matters: First, during pregnancy, you should go to the designated hospital for regular pregnancy checkups, including liver function series indicators, blood routine, ultrasound, etc., to understand the changes in the liver, if the liver function is obviously abnormal and the body feels particularly uncomfortable, you should decide whether to continue the pregnancy after a joint consultation with doctors of the relevant departments. Secondly, special attention should be paid to the use of medication during pregnancy, and try to avoid the use of drugs that have toxic effects on the liver, such as hypoglycemic drugs, anti-tuberculosis drugs, hormone drugs, antibiotic drugs and some Chinese medicines. Third, after 36 weeks of pregnancy, sexual life should be absolutely prohibited to prevent miscarriage, premature rupture of membranes and intrauterine infection. Fourth, rationalize the dietary structure, do not blindly supplement, do not use a variety of health care nutritional supplements, in order to prevent them from mixing hormones and other harmful substances. Advocating balanced nutrition, the amount of food should be moderate, to avoid excessive weight gain, the formation of fatty liver. Finally, during pregnancy, you can use some safe liver-protecting medicines under the guidance of your doctor, such as liver-protecting tablets and compound liver-protecting spirit. During pregnancy, if there is obvious fatigue, loss of appetite, dark yellow urine, yellow eyes and other abnormal manifestations, you should go to the hospital in time to confirm the diagnosis. Breastfeeding is not recommended for mothers with “triple positive” Breastmilk is rich in nutrients and antibodies against pathogens, and whether it can be breastfed depends on the situation, and mothers with hepatitis B need to develop hygienic habits such as washing hands and nipples before breastfeeding. Although hepatitis B virus can be transmitted through breast milk, newborns are usually immunized immediately after delivery, and usually do not transmit the virus through breast milk. In addition, breastfeeding is generally not recommended for mothers with “major triple positive”; mothers with “minor triple positive” can breastfeed their babies with lower viral loads, and the babies have been immunized with Hepatitis B vaccine and Hepatitis B immunoglobulin. If breastfeeding brings excessive burden to the mother and aggravates her condition, it is better to stop breastfeeding. In addition, mothers in the acute stage of hepatitis should not bring their children by themselves. Mothers recovering from hepatitis should practice good hygiene, wash their hands frequently, and not feed their children from mouth to mouth; and as long as the child is vaccinated against hepatitis B immediately after birth, there is no obstacle for mothers to bring up their children. It would be ideal to be able to have access to the child after the disease has recovered.