Complications of UTI The main threat is the development of untreated UTI spreading to one or both kidneys. When the germ attacks the kidney, permanent effects on renal function may remain. If the patient already has an underlying kidney lesion of his own, this aggravation may lead to the consequences of renal failure. There is also the small but very dangerous chance that the infection will enter the bloodstream and spread to other organs and organs. How UTI starts There are many bacteria in our intestinal and genital areas, however none in the urinary system, and in fact the urine is sterile. UTI can be caused when bacteria present in the body, such as E. coli, happen to enter the urinary system. the typical route is for the bacteria to enter the bladder through the urethra, and women are more susceptible than men, probably because they have a shorter urethra. What increases your risk of UTI UTI is most common in sexually active women. Other factors that increase the risk include not drinking enough water, frequent bathing, holding urine for too long and kidney stones.