The treatment of diabetic nephropathy focuses on the following aspects: (1) Lifestyle changes, such as reasonable weight control, diabetic diet, smoking cessation and appropriate exercise, etc. (2) Low protein diet, if renal function is normal, dietary protein intake is 0.8g/(kg-d), if renal function has decreased, dietary protein intake is recommended to be 0.6 to 0.8g/(kg-d), mainly high quality animal protein. (3) Control blood glucose, priority can be given to glucose-lowering drugs with less excretion from the kidney, and patients with severe renal insufficiency should be treated with insulin. (4) Control blood pressure. ACEI or ARB is preferred as the antihypertensive drug, and other antihypertensive drugs can be added for those with poor blood pressure control. (5) Correct dyslipidaemia, statins may be given. (6) To control proteinuria, renin-angiotensin system (RAS) inhibitors (ACEI or ARB drugs) are preferred to reduce urinary albumin. (7) If the condition deteriorates leading to renal failure, dialysis treatment and renal transplantation may be indicated if necessary.